Session

Preclinical innovation: Latest news in future treatment of erectile dysfunction

Poster Session 70

  • Location:
    Room 14b (ICM, Level 1)
  • Chairs:
     F. Fusco, Naples (IT)
     A. Muneer, London (GB)
  • Aims and objectives of this session

    The session will include animal studies with stem cell based interventions for erectile dysfunction. Furthermore, latest news in regeneration of pelvic nerves and the role of endothelial and smooth muscle in erectile dysfunction will be presented. The audience will walk away with an idea of what may lie ahead in the world of andrology.

  • Poster viewing of 20 minutes. Presentations will take place on stage. Standard presentations are 2 minutes in length, followed by 2 minutes for discussion.
880
Combination therapy using human adipose-derived stem cells on the cavernous nerve and low-energy shockwaves on the corpus cavernosum in a rat model of postprostatectomy erectile dysfunction

By: Kwon O., Choi J.B., Park Y.H., Cho H.J., Ha U-S., Hong S.H., Kim S.W., Lee J.Y.

Institutes: Seoul St. Mary’s Hospital, Dept. of Urology, Seoul, South Korea

881
Tissue sealing sheet attenuates erectile dysfunction after nerve-sparing surgery in a rat model

By: Yamashita S., Kamiyama Y., Fujii S., Endo E., Kawasaki Y., Izumi H., Kawamorita N., Mitsuzuka K., Adachi H., Kaiho Y., Ito A., Arai Y.

Institutes: Tohoku University Graduate School of Medicine, Dept. of Urology, Sendai, Japan

882
Damage and repair processes of cavernous nerve after crushing injury in rat model - evidence of transmission electron microscopy in correlation with serial intracavernous pressure and molecular histological change

By: Wu Y-N.1, Liao C-H.2, Shang H-S.3, Chiang H-S.1

Institutes: 1Fu Jen Catholic University, Graduate Institute of Basic Medicine, New Taipei City, Taiwan, 2Fu Jen Catholic University, School of Medicine, New Taipei City, Taiwan, 3Tri-Service General Hospital, Dept. of Clinical Pathology, Taipei City, Taiwan

883
Ganglion cell size after bilateral cavernous nerve resection and reconstruction

By: May F.1, Buchner A.2, Brinkmann K.3, Weidner N.4, Stief C.2, Matiasek K.3

Institutes: 1Private Practice, Dept. of Urology, Dachau, Germany, 2Ludwig-Maximilians-University, Dept. of Urology, Munich, Germany, 3Ludwig-Maximilians-University, Dept. of Clinical and Comapartive Neuropathology and Clinical Veterinary Medicine, Munich, Germany, 4Ruprechts-Karls-University, Dept. of Spinal Cord Injury Centre, Heidelberg, Germany

885
Osteopontin is an important player in endogenous neuroregeneration after cavernous nerve injury

By: Weyne E.1, Matsui H.2, Hannan J.3, Fabio C.4, Liu X.2, Van Der Aa F.1, Bivalacqua T.2, Albersen M.1

Institutes: 1UZ Leuven, Dept. of Urology, Leuven, Belgium, 2Johns Hopkins, Dept. of Urology, Baltimore, United States of America, 3East Carolina University, Dept. of Physiology, Greenville, United States of America, 4San Rafaelle, Dept. of Urology, Milan, Italy

886
Improvement of erectile function by suppression of corporal fibrosis with LIM-kinase2 inhibitors in a rat model of cavernous nerve injury

By: Jung G.1, Kim B.S.1, Song W.H.1, Park J.1, Park K.1, Kim S.W.1, Paick J-S.1, Ryu K.H.3, Cho S.Y.2, Jeong H.2, Son H.2, Cho M.C.2

Institutes: 1Seoul National University Hospital, Dept. of Urology, Seoul, South Korea, 2SMG-SNU Boramae Medical Center, Dept. of Urology, Seoul, South Korea, 3Gwangmyeong Sungae Hospital, Dept. of Urology, Gwangmyeong, South Korea

887
SDF-1 treatment facilitates axonal regeneration from the major pelvic ganglion in a dose-dependent fashion

By: Sopko N., Matsui H., Kates M., Xiaopu L., Bivalacqua T.

Institutes: The Johns Hopkins School Of Medicine, Dept. of Urology, Baltimore, United States of America

888
Effects of eupatilin on the contractility of corpus cavernosal smooth muscle through nitric oxide independent pathways

By: Choo S.H.1, Lee S.W.2, Kim J.J.2, Sung H.H.2, Chae M.R.2, Kang S.J.2, Han D.H.2, So I.3, Lee S.W.2

Institutes: 1Ajou University School of Medicine, Dept. of Urology, Suwon-Si, South Korea, 2Samsung Medical Center, Sungkyunkwan University School of Medicine, Dept. of Urology, Seoul, South Korea, 3Seoul National University College of Medicine, Dept. of Physiology, Seoul, South Korea

889
Effect of the BKCa channel opener LDD175 on the erectile function of in vivo diabetic rat model

By: Lee S.W.1, Sung H.H.1, Chae M.R.1, Kang S.J.1, Han D.H.2, Park J.K.2, Lee S.W.1

Institutes: 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Dept. of Urology, Seoul, South Korea, 2Chonbuk National University School of Medicine, Dept. of Urology, Jeonju, South Korea

890
Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase

By: Zhang Y.1, Wang T.1, Yang J.1, Li R.1, Chen Z.2, Wang S.1, Liu J-H.1, Ye Z.1

Institutes: 1Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Dept. of Urology, Wuhan, China, 2Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Dept. of Geriatrics, Wuhan, China

891
Erectile dysfunction correlates with hyperhomocysteinemia: International Index of Erectile Function (IIEF) and penile Doppler ultrasound evaluation

By: Busetto G.M., Giovannone R., Antonini G., Del Giudice F., Tricarico S., Ragonesi G., Gentile V., De Berardinis E.

Institutes: Sapienza Rome University Policlinico Umberto I, Dept. of Urology, Rome, Italy

892
Sub-albuginean adipocyte accumulation is associated with erectile dysfunction: First clinical evidence and pathophysiological implications

By: Vinay J.1, Sarquella J.1, Sanchez J.1, Algaba F.2, Gallegos I.3, Rojas-Cruz C.5, Palma C.4

Institutes: 1Fundació Puigvert, Dept. of Andrology, Barcelona, Spain, 2Fundació Puigvert, Dept. of Pathology , Barcelona, Spain, 3University of Chile Clinical Hospital, Dept. of Pathology , Santiago, Chile, 4University of Chile Clinical Hospital, Dept. of Urology, Santiago, Chile, 5FOSCAL, Clínica Carlos Ardila Lulle, Dept. of Urology, Bucaramanga, Colombia

893
Simvastatin treatment improves endothelial function in the corpus cavernosum in uremic apolipoprotein E deficient mice

By: Ivanovski O.1, Nikolov I.2, Davceva O.3, Petrushevska G.4

Institutes: 1Medical Faculty, University ss Cyril and Methodius, Dept. of Urology, Skopje, Macedonia, 2Medical Faculty, University ss Cyril and Methodius, University Clinic of Nephrology, Skopje, Macedonia, 3Medical Faculty, University ss Cyril and Methodius, University Clinic of Clinical Biochemistry, Skopje, Macedonia, 4Medical Faculty, University ss Cyril and Methodius, Dept. of Pathology, Skopje, Macedonia

894
A novel therapeutic strategy for patients with premature ejaculation: Possibility of electrical stimulation of dorsal penile nerves

By: Kimura Y., Saitoh C.

Institutes: Astellas Pharma Inc., Evolving Medical Solutions, Tsukuba-Shi, Japan