Session

Current risk stratification and adapted strategies for the management of upper tract urothelial carcinomas

Poster Session 64

  • Location:
    Room Vienna (Hall B2, level 0)
  • Chairs:
     W.C. Loidl, Linz (AT)
     V. Pansadoro, Rome (IT)
  • Aims and objectives of this session

    Upper Tract Urothelial Carcinoma (UTUC) are relatively uncommon compared to bladder cancer, but 60% of UTUCs are invasive at diagnosis. The risk stratification appears to be crucial to elaborate appropriate strategy and select patients for kidney-sparing management. The purpose of the session is to provide an overview of available assessment tools and treatments.

  • Poster viewing of 20 minutes. Presentations will take place on stage. Standard presentations are 2 minutes in length, followed by 2 minutes for discussion. Extended presentations (*) are 3 minutes in length, followed by 3 minutes for discussion.
800
Oncological outcomes of radical nephroureterectomy versus kidney-sparing surgery for elective treatment of clinically organ-confined upper tract urothelial carcinoma of the distal ureter

By: Seisen T.1, Nison L.2, Remzi M.3, Klatte T.4, Lucca I.4, Mathieu R.5, Bozzini G.6, Capitanio U.7, Novara G.8, Cussenot O.9, Compérat E.10, Renard Penna R.11, Peyronnet B.12, Merseburger A.13, Fritsche H-M.14, Hora M.15, Shariat S.4, Colin P.16, Rouprêt M.12

Institutes: 1Hôpitaux universitaires La Pitié-Salpêtrière, Dept. of Urology, Paris, France, 2Hôpitaux Universitaires Lille, Dept. of Urology, Lille, France, 3Landesklinikum Korneuburg, Dept. of Urology, Korneuburg, Austria, 4Medical University Vienna, Dept. of Urology, Vienna, Austria, 5Medical University Vienna, Dept. of Urology, Vienna, France, 6Medical University Lille, Dept. of Urology, Lille, France, 7IRCCS Ospedale San Raffaele University, Dept. of Urology, Milan, Italy, 8Urology Clinic, University of Padua, Dept. of Urology, Padua, Italy, 9Tenon Hospital, Dept. of Urology, Padua, Italy, 10Pitié Salpétrière Hospital, Dept. of Pathology, Paris, France, 11Pitié Salpétrière Hospital, Dept. of Radiology, Paris, France, 12Pitié Salpétrière Hospital, Dept. of Urology, Paris, France, 13University Hospital Schleswig-Holstein, Dept. of Urology, Lübeck, Germany, 14St Josef Medical Center, University of Regensburg, Dept. of Urology, Regensburg, Germany, 15Faculty Hospital Plzeň and Charles University In Prague, Dept. of Urology, Prague, Czech Republic, 16Private Hospital La Louvière, Dept. of Urology, Lille, France

801
The impact of ureteral ligation on clinical outcome during radical nephroureterectomy for upper urinary tract urothelial carcinoma: Multi-institutional case series study JCOG1110A

By: Inokuchi J.1, Kuroiwa K.2, Naito S.1, Kakehi Y.3, Sugimoto M.3, Tanikawa T.4, Fujimoto H.5, Gotoh M.6, Masumori N.7, Ogawa O.8, Etoh M.9, Ohyama C.10, Yamaguchi A.11, Matsuyama H.12, Ichikawa T.13, Asano T.14, Takenaka A.15, Fujimoto K.16, Yamaguchi R.17, Habuchi T.18, Hashine K.19, Arai Y.20, Nagaoka A.21, Nishiyama H.22, Shinohara N.23, Niwakawa M.24, Egawa S.25, Ozono S.26, Kawano Y.27, Ishizuka O.28, Nishimura K.29, Tochigi T.30, Sugimura Y.31, Mizusawa J.32, Eba J.32

Institutes: 1Kyushu University, Dept. of Urology, Fukuoka, Japan, 2Miyazaki Prefectural Miyazaki Hospital, Dept. of Urology, Miyazaki, Japan, 3Faculty of Medicine, Kagawa University, Dept. of Urology, Kagawa, Japan, 4Niigata Cancer Center Hospital, Dept. of Urology, Niigata, Japan, 5National Cancer Center Hospital, Dept. of Urology , Tokyo, Japan, 6Nagoya University Graduate School of Medicine, Dept. of Urology, Tokyo, Japan, 7Sapporo Medical University School of Medicine, Dept. of Urology, Sapporo, Japan, 8Kyoto University, Dept. of Urology, Kyoto, Japan, 9Graduate School of Medical Sciences, Kyushu University, Dept. of Urology, Fukuoka, Japan, 10Hirosaki University Graduate School of Medicine, Dept. of Urology, Hirosaki, Japan, 11Harasanshin Hospital, Dept. of Urology, Fukuoka, Japan, 12Graduate School of Medicine, Yamaguchi University, Dept. of Urology, Ube, Japan, 13Graduate School of Medicine, Chiba University, Dept. of Urology, Chiba, Japan, 14National Defense Medical College, Dept. of Urology, Tokorozawa, Japan, 15Tottori University Faculty of Medicine, Dept. of Urology and Surgery, Yonago, Japan, 16Nara Medical University, Dept. of Urology, Kashihara, Japan, 17Teikyo University School of Medicine, Dept. of Urology, Tokyo, Japan, 18Akita University Graduate School of Medicine, Dept. of Urology, Akita, Japan, 19Shikoku Cancer Center Hospital, National Hospital Organization, Dept. of Urology, Matsuyama, Japan, 20Tohoku University Graduate School of Medicine, Dept. of Urology, Sendai, Japan, 21Yamagata University Hospital, Dept. of Urology, Yamagata, Japan, 22Faculty of Medicine, University of Tsukuba, Dept. of Urology, Ibaraki, Japan, 23Hokkaido University Graduate School of Medicine, Dept. of Urology, Sapporo, Japan, 24Shizuoka Cancer Center, Dept. of Urology, Shizuoka, Japan, 25Jikei University School of Medicine, Dept. of Urology, Tokyo, Japan, 26Hamamatsu University School of Medicine, Dept. of Urology, Hamamatsu, Japan, 27Graduate School of Medical Sciences, Kumamoto University, Dept. of Urology, Kumamoto, Japan, 28Shinshu University School of Medicine, Dept. of Urology, Matsumoto, Japan, 29Osaka Medical Center For Cancer and Cardiovascular Diseases, Dept. of Urology, Osaka, Japan, 30Miyagi Cancer Center, Dept. of Urology, Natori, Japan, 31Mie University Graduate School of Medicine, Dept. of Nephro-Urologic Surgery and Andrology, Tsu, Japan, 32National Cancer Center, JCOG Data Center / Operations Office, Tokyo, Japan

802
Risk stratification by means of the biological age related factors better predicts cancer-specific survival than the chronological age in patients with upper tract urothelial carcinoma (UTUC): A multi-institutional database study

By: Inamoto T.1, Takahara K.1, Matsuyama H.2, Fujimoto K.3, Shiina H.4, Sakano S.2, Nagao K.2, Miyake M.3, Tatsumi Y.3, Yasumoto H.4, Azuma H.1

Institutes: 1Osaka Medical College, Dept. of Urology, Osaka, Japan, 2Yamaguchi University, Dept. of Urology, Ube, Japan, 3Nara Medical University, Dept. of Urology, Kashihara, Japan, 4Shimane University School of Medicine, Dept. of Urology, Izumo, Japan

803
Risk stratification model for lymphovascular invasion, pathological T stage, lymph node involvement, and c-reactive protein predicts high-risk patients - who are candidate for adjuvant chemotherapy in upper urinary tract urothelial cancer

By: Nagao K.1, Matsuyama H.1, Fujimoto K.2, Azuma H.3, Shiina H.4, Tatsumi Y.2, Sakano S.1, Inamoto T.3, Yasumoto H.4

Institutes: 1Graduate School of Medicine, Yamaguchi University, Dept. of Urology, Ube, Japan, 2Nara Medical University, Dept. of Urology, Kashihara, Japan, 3Osaka Medical College, Dept. of Urology, Takatsuki, Japan, 4Shimane University Faculty of Medicine, Dept. of Urology, Izumo, Japan

804
Promising role of preoperative neutrophil-to-lymphocyte ratio in patients treated with radical nephroureterectomy

By: Vartolomei M.D.1, Mathieu R.2, Rouprêt M.3, Lucca I.4, Mbeutcha A.2, Seitz C.2, Karakiewicz P.5, Fajkovic H.2, Rink M.6, Briganti A.7, Xylinas E.8, Shariat S.2

Institutes: 1Medical University Vienna and University of Medicine and Pharmacy, Dept. of Cell and Molecular Biology, Targu Mures, Romania, 2Medical University and General Hospital, Dept. of Urology, Vienna, Austria, 3Faculté De Médecine Pierre Et Marie Curie, University Paris 6, Dept. of Urology, Paris, France, 4Centre Hospitalier Universitaire Vaudois, Dept. of Urology, Lausanne, Switzerland, 5University of Montreal Health Centre, Dept. of Cancer Prognostics and Health Outcomes, Montreal, Canada, 6University Medical Center Hamburg-Eppendorf, Dept. of Urology, Hamburg, Germany, 7Vita Salute San Raffaele University, Dept. of Urology, Milan, Italy, 8Cochin Hospital, Assistance Publique-Hôpitaux De Paris, Paris Descartes University, Dept. of Urology, Paris, France

805
International multicentre validation of prognostic micrornas in upper tract urothelial carcinoma

By: Izquierdo Reyes L.1, Montalbo R.1, Ramirez-Backhaus M.2, Solsona E.2, Rubio J.2, Van Der Heiden T.3, Schaafsma H.3, Lopez-Beltran A.4, Blanca A.4, Mengual L.1, Alcaraz A.1

Institutes: 1Hospital Clínic de Barcelona, Dept. of Urology, Barcelona, Spain, 2Fundacion IVO, Dept. of Urology, Valencia, Spain, 3Radbou University Centre, Dept. of Urology, Nijmegen, The Netherlands, 4Hospital Reina Sofia, Dept. of Urology, Cordoba, Spain

806
Chronological changes of clinical outcome after radical nephroureterectomy in patients with localized upper urinary tract carcinoma treated in the last two decades: Are we succeeding?

By: Makito M.1, Tatsumi Y.1, Fujimoto K.1, Nagao K.2, Sakano S.2, Matsuyama H.2, Inamoto T.3, Azuma H.3, Yasumoto H.4, Shiina H.4

Institutes: 1Nara Medical University, Dept. of Urology, Nara, Japan, 2Graduate School of Medicine, Yamaguchi University, Dept. of Urology, Yamaguchi, Japan, 3Osaka Medical College, Dept. of Urology, Osaka, Japan, 4Shimane University School of Medicine, Dept. of Urology, Shimane, Japan

807
Long-term results of flexible ureteroscopy and laser photoablation for the treatment of patients with upper tract urothelial carcinoma: In whom an endourological management may not be enough to control the disease?

By: Villa L.1, Cloutier J.2, Salonia A.3, Montorsi F.3, Traxer O.2

Institutes: 11 Tenon Hospital, Pierre and Marie Curie University, Paris, France 2 Division of Experimental Oncolo, Dept. of Urology, Milan, Italy, 2Tenon Hospital, Pierre and Marie Curie University, Paris, France, Dept. of Urology, Paris, France, 31 Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele 2 Università, Dept. of Urology, Milan, Italy

808
Prognostic value of the pT3 subclassification for upper tract urothelial carcinomas of the renal pelvicalyceal system

By: Seisen T.1, Compérat E.2, Colin P.3, Rioux-Leclerq N.4, Peyronnet B.5, Bensalah K.5, Pfister C.6, Gobet F.7, De La Taille A.8, Allory Y.9, Xylinas E.10, Sibony M.11, Cussenot O.12, Rouprêt M.13

Institutes: 1Hôpitaux universitaires La Pitié-Salpêtrière, Dept. of Urology, Paris, France, 2Hôpitaux universitaires La Pitié-Salpêtrière, Dept. of Pathology, Paris, France, 3Hôpital Privé De La Louvière, Dept. of Urology, Lille, France, 4Hôpital Universitaire De Rennes, Dept. of Pathology, Rennes, France, 5Hôpital Universitaire De Rennes, Dept. of Urology, Rennes, France, 6Hôpital Universitaire De Rouen, Dept. of Urology, Rouen, France, 7Hôpital Universitaire De Rouen, Dept. of Pathology, Rouen, France, 8Hôpital Universitaire Henri Mondor, Dept. of Urology, Créteil, France, 9Hôpital Universitaire Henri Mondor, Dept. of Pathology, Créteil, France, 10Hôpital Universitaire Cochin, Dept. of Urology, Paris, France, 11Hôpital Universitaire Cochin, Dept. of Pathology, Paris, France, 12Hôpital Universitaire Tenon, Dept. of Urology, Paris, France, 13Hôpital Universitaire Pitié Salpétrière, Dept. of Urology, Paris, France

809
Prognostic significance of sarcopenia in upper tract urothelial carcinoma patients who underwent radical nephroureterectomy

By: Fukushima H., Nakanishi Y., Kataoka M., Tobisu K., Koga F.

Institutes: Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Dept. of Urology, Tokyo, Japan

810
Neutrophil-to-lymphocyte ratio may predict recurrence in urothelial carcinoma of the urinary bladder: A prospective trial

By: Bahouth Z.1, Getzler I.1, Mano R.2, Baniel J.2, Nativ O.1, Rubinstein J.3, Halachmi S.1

Institutes: 1Bnai-Zion Medical Center, Dept. of Urology, Haifa, Israel, 2Rabin Medical Center, Dept. of Urology, Petach-Tekva, Israel, 3Technion – Institute of Technology, Dept. of Mathematics, Haifa, Israel

* 811
The utility of diffusion-weighted MRI as an imaging biomarker of upper urinary tract cancer: A preoperative prognostic indicator reflecting histological grade

By: Yoshida S.1, Uchida Y.1, Kobayashi S.1, Koga F.1, Tanaka H.2, Yokoyama M.1, Ishioka J.1, Matsuoka Y.1, Saito K.1, Fujii Y.1, Kihara K.1

Institutes: 1Tokyo Medical and Dental University Graduate School, Dept. of Urology, Tokyo, Japan, 2Ochanomizu Surugadai Clinic, Dept. of Radiology, Tokyo, Japan

813
Impact of an adjuvant chemotherapeutic regimen on the clinical outcome in high-risk patients with upper tract urothelial carcinoma

By: Shirotake S.1, Kikuchi E.2, Tanaka N.2, Matsumoto K.2, Miyazaki Y.2, Kobayashi H.2, Ide H.2, Obata J.2, Hoshino K.2, Kosaka T.2, Kanao K.2, Miyajima A.2, Nakagawa K.2, Oyama M.1, Oya M.2

Institutes: 1Saitama International Medical Center, Dept. of Urology, Hidaka City, Saitama, Japan, 2Keio University School of Medicine, Dept. of Urology, Shinjuku, Tokyo, Japan